Showing posts with label Shopping. Show all posts
Showing posts with label Shopping. Show all posts

Thursday, September 27, 2012

Collagen: Uncovers Anti Aging Research

English: Synthesis of collagen, schematic
English: Synthesis of collagen, schematic (Photo credit: Wikipedia)

From facial peelers to lip treatments to wrinkle fighters, injections, and micro current treatments, collagen is the main line ingredient in anti-aging preparations today. And it is no wonder why. Collagen's role in the aging process is well confirmed. Forming 80% of the connections in the skin, collagen makes up the connective network that supports its cellular structure. Over time, however, at the deepest molecular level, the proteins that connect skin cells slowly diminish in quantity and become thin (stripped down), as do the skin's youthful characteristics. After the age of 25 the molecular structures of these large proteins change and become less able to serve their function. The biological processes that manufacture these large collagen proteins no longer produce them as readily as they once did.

Collagen is of great interest to researchers today because of its ubiquitous nature in the structure of skin and its role in the aging process. Collagen is the most abundant protein, forming strong sheets and cables that support the structure of skin, internal organs, cartilage and bones, as well as all the connective tissue in between. Existing in 80% of the connections of the skin, this master protein is the subject of the millions of dollars spent on collagen research each year. Collagen fibrils of skin are also ever changing, eventually giving way to the signs of aging. Not only do skin cells produce less of it over time, they produce less accurate copies of it. This two-fold process is the fundamental cause of aging and its effects.

However, not all collagen extractions display equal effectiveness. The complications involved in procuring this master protein in its active state, make it difficult for cosmetic and pharmaceutical companies to manufacture. Because of this, concentrations and quality of collagen are tentative--most products containing less than 3% of it as an ingredient, which remains inactive to the biological processes that use it.

Just recently, however, a team of researchers working extensively in an independent study is perhaps the first to understand the importance of biochemical activity in collagen proteins. Through these studies, researchers and chemists, at the institute of chemistry in Gdansk, have extracted a "living" collagen preparation demonstrating an unprecedented ability to fight the cause of aging. The study will quite possibly put a new spin on anti aging skin care today.

While many opponents of collagen treatments insist that collagen cannot absorb into the skin, this independent study in collagen research reveals a new development with the ability to do so. Clearly the high concentration, trans-dermal absorptivity, and biochemical activity do in some way contribute to collagen's effectiveness, despite the fact that previous collagen extractions lack the ability to absorb and be recognized by the biological processes that use it.

Perhaps the most salient attribute of biologically active collagen compounds is their ability to unify with the tightly meshed, cellular matrix of skin that would normally block absorption. The structural similarity of the active protein to that of the skin's proteins acts as an admission ticket to the biological processes that use it, allowing the product to absorb and effectively supplement diminished collagen levels.

Still, the effectiveness of the newly formulated collagen preparation is gaining wide currency in the minds of consumers as an effective means to prevent the signs of aging. As Harry Klenda, President and CEO of Baltic Collagen points out, collagen in its purest and active state is shown to be a multi-factorial solution to the developing cause of aging.
"The only way to really distinguish the efficacy of activated collagen is by substantiating marketing claims with experimental evidence and rigorous clinical trials. Through this methodology, the efficacy of biochemically active collagen is well confirmed. Experimental evidence supports that biochemical activity of applied collagen causes significant changes to the skin's aging properties."
In a controlled study involving 20 participants testing the effectiveness of the bio-active collagen, each respondent noted immediate differences from the moment of application: increased firmness, lifted wrinkles, smoothened skin surface, restored slack and notable differences in elasticity. The control group applying an inactive collagen compound reported no such differences. The respondents who continued a four-week treatment regimen using the biologically active collagen noted cumulative changes in their appearance. Results of long-term usage were measured through a combination of input mediums, such as before/after pictures, concurring opinions from a variety of experts, dermal thickness measurements and subjective judgments of results obtained.

Through Clinical trials and experimentation conducted at the institute of chemistry in Gdansk, biochemically active collagen has been experimentally identified to work in six different ways. From the moment of application, the user's skin undergoes an unparalleled lifting effect. In doing so, wrinkles diminish and skin becomes notably thicker, firmer, smoother, and more elastic. And because wrinkles emerge due to lack of flexibility in skin, increasing elasticity shields against the developing cause of aging.

Besides the obvious advantages of restoring flexibility and diminished collagen levels, experimental evidence supports that this activated collagen "creates an environment that makes collagen producing cells (fibroblasts) more active, thereby increasing one's own collagen production," an article in the Archives of Dermatology confirms.

Follow up studies conducted at the University of Michigan use Nuclear Magnetic Resonance Spectroscopy to study the fibroblast growth factor proteins in solution. Through these studies, a newly stabilized, yet active collagen molecule is confirmed to quite possibly mark the first generation of anti aging skin care products to target the direct cause of aging.

However, before May of 2009, previous versions of biochemically active collagen were not yet a sensational discovery. In 2002, the preliminary research arrived at an active collagen preparation with reservations that it only displayed biochemical activity in temperature limits of 41 and 59 degrees Fahrenheit. Beyond that, the collagen molecule would break apart into fragmented segments. It was a major problem to researchers; however, follow up studies continued until another major technological advance came underway, which led the project into a new direction.

In 2009, the first producers of the activated compound discovered a more sophisticated collagen preparation, with dramatic healing properties. Owed to a patented technology, the collagen molecule was successfully stabilized (held together) by a reinforcing mechanism, using hydroxyproline-a hydrogen bonded reinforcing mechanism that combines with the collagen molecule, holding it together. The hydroxylated version of the amino acid, proline, is a major component of the collagen protein. And when successfully combined and cross-linked with collagen, it reinforces the large molecule, keeping its structural integrity intact and its most valuable properties alive.

The powerful intermolecular forces (hydrogen bonding) that reinforce the molecular structure of are the same active forces that attract the molecule to the protein matrix of skin. The points of attraction act as chemical handles that latch onto the skin's cellular matrix like a magnet, pulling it tight and reinforcing the underlying protein configurations whose shortage allows skin cells to fall out of alignment.

Besides the ability to unify with and absorb into the skin's cellular network, as Harry Klenda, president of BCI points out, clinical research indicates that the patented collagen compound neutralizes and protects against free radical damage.
"It is no surprise that free radicals accelerate the aging process. The human body is made up of specialized cells that each perform a specific function. As one ages free radicals, known as aggravated atoms or molecules, slowly damage neighboring cells. When a free radical attacks a nearby atom it steals an electron to become stable. But by taking an electron from another chemical, the donating molecule becomes a free radical itself, and the process repeats. The chain reaction (known as propagation) can be thousands of events long. This is damage, and each event ages one's appearance everyday."
However, further experimental evidence suggests that a free radical does little damage when attacking a "loose" protein or other molecule in the body whereas a free radical attacking an integrated collagen protein of the skin causes a break in the collagen strand. Once the proteins of skin obtain multiple breaks, it loses its elastic quality. Skin becomes thin and limp.

Cells on the outer epidermal layer of skin are each subjected to 5,000 free radical attacks every day. And because the number of damaged cells is constantly increasing, so is the demand for antioxidants. But as the ability to produce antioxidants in ones own defense diminishes, the aging process speeds up every year.

Experimental evidence supports that collagen in its active state protects against free radical damage in two ways, reports Harry Klenda, President of BCI: It acts as a sacrificial target of free radical attacks, and seals out pollution generated free radicals in the environment. The preparation attracts internally created radicals like a magnet, while shielding externally introduced free radicals from moving across the dermal barrier.
"The applied collagen [loose collagen protein] gets attacked before free radicals make their way into the internally attached collagen proteins of skin; it also seals out environmental stressors that cause aging: pollution, heavy metals, and biochemical processes. It is a synchronized complex with dual (overlapping) antioxidant action; everyday that one applies an activated collagen is a day that the skin does not age."
By analyzing the benefits of biochemical activity, purity, and absorptivity, it appears that new advances in the cosmetic industry may prosper significantly from this new finding in collagen research. Through these studies, a newly stabilized, yet active collagen molecule has emerged with the unprecedented ability to absorb and combine with aged proteins--quite possibly marking the first generation of skin care products to target the direct cause of aging as opposed to the effects. Clinical results bring promising findings to universal applications in the medical industry as well.

John Rathers is a syndicated columnist who writes for chemistry journals and a variety of other purposes. Mr. Rathers graduated from Southern Polytechnic State University with a Bachelor of Science in Business Administration with a minor in Chemistry and a minor in Spanish. Currently he works in public relations, and owns a business in technical writing.

Alex, Carl A. "Skin Free Radical Damage." 4 Sept. 2008. Web. 16 July 2010.

Fisher, Gary J., John J. Voorhees, and James Varani. "Looking Older: Fibroblast Collapse and Therapeutic Implications." Archives of Dermatology, a Monthly Peer-reviewed Medical Journal Published by AMA. 7 May 2008. Web. 12 June 2010.

Klenda, Harry M. "What Is Collagen?" Baltic Collagen. 13 June 2009. Web. 14 July 2010.

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Marketing Weight Loss As Your Home Business

AURORA, CO - NOVEMBER 20:  Zoe McCoy, 9, lifts...
AURORA, CO - NOVEMBER 20: Zoe McCoy, 9, lifts weights in exercise class during the Shapedown program for overweight adolescents and children on November 20, 2010 in Aurora, Colorado. The 10-week family-centered program held by the Denver area Children's Hospital teaches youth and their parents ways to lead a healthier more active lifestyle, as a longer lasting weight-loss alternative to dieting. Nationally, some 15 percent of children are overweight or obese, as are some 60 percent of adults. (Image credit: Getty Images via @daylife)

You tell yourself when you are in doubt; you can't do this. Who cares about what others think and what gives them the right to judge? This is some of the crap we feed ourselves as we put on the pounds or avoid getting starting at owning your business. We stop looking in full length mirrors knowing you still look good from the neck up and your unemployment hasn't run out yet. It is also what you think when others put you down for marketing on- line when you don't make money when you start out.

We think about others judging us and assuming we know what they think. Truth is that no one really cares. You would think your spouse should care, but he or she doesn't notice. My husband and children don't have more than one thought at a time and it usually is about them. My health and wealth is my responsibility. My responsibility is to myself and my family. Change the thought change the person from the inside out.

When you see an old friend and they are so glad to see you, they ask about everything except your weight. They are never interested in hearing about the marketing business and they are your friend so they will let you ramble on just don't throw your pitch at them. They will ask if they want more information. The only one that can make you feel bad about yourself is you. Why beat yourself up on what others may think of you. If you don't look at yourself in a full length mirror you are the only one that can change it. Don't be afraid of what you see and you might decide to do something about. Wouldn't you rather have walked away feeling the pleasure of the visit, feeling comfortable in your own skin and confident in who you are. You are a marketer so offering them a product that you know will help them solve a problem.

I'm fifty-one, I look at myself everyday in a full length mirror, I try to change the things I need work on. Every day I am improving, every day I learn something new about myself and my business. I know what my friends and family think of me. As you get older things that matter change for all of us and everyone's need are different. Some of us want to age gracefully and others will fight it tooth and nail. Then there are those of us who want to take charge of our wealth and build our own business but are afraid to get started. The fact is you have to do what's best for you. Take a good long look at yourself from top to bottom, if what you see is working for you, great. If not change it!

You can improve, if you really want to. There are companies that can sell you health in a bottle and have it delivered to your front door. The best part of these companies is the products; they let the science back up the products and the testimony by pleased customers who have found the answers that they are looking for. The opportunities with these companies are great if you are will to work for your future. They supply you with a web site, training by the top earners in the company and compensation plans to support you. Now you are on your way to creating a business.

So many people are looking for products that support their weight loss efforts. I work directly with some of these companies. These companies are great; each has a weight loss program different from the other, they all are great tools to help you with your weight loss efforts, I know that when you find something that you like, you want to share it with everyone you come in contact with. So get paid for your recommendations. There are so many people looking for away to start a home business and companies that put your health first.

I am a marketer and I can tell you this it does not matter what product you use to help support your weight loss. First you must check with your doctor and run the product information by them. Then you must stop making excuses, weight loss and marketing both take a lot of work and your choice to join the marketing community is not something you should do if your heart is not in it. The choices you make in business have to come from the knowledge you gain and the training you apply. Remember if you want it bad enough you will use these products and the weight loss programs as a tool to gain success. You know that there is no magic pill for weight loss and there is no business that becomes successful without working hard at it. Good Luck with both your weight loss and your business choices.

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